"After 12 weeks in the Low-molecular-weight Collagen peptide group, visual assessment score and three parameters of skin wrinkling were significantly improved compared with the placebo group.Direct effects of collagen peptides on fibroblasts, M2- like macrophages, and oral tolerance-related mechanisms are the possible mechanisms for the beneficial effects of collagen supplementation." three different mechanisms of action were clarified for the intervention. "This study demonstrated that the use of the collagen hydrolysate with a higher content of Pro-Hyp and Hyp-Gly led to more improvement in facial skin conditions, including facial skin moisture, elasticity, wrinkles and roughness.".With regard to skin moisture and skin evaporation, a positive influence of CH treatment could be observed in a subgroup analysis, but data failed to reach a level of statistical significance." After 4 weeks of follow-up treatment, a statistically significantly higher skin elasticity level was determined in elderly women. "At the end of the study, skin elasticity in both CH dosage groups showed a statistically significant improvement in comparison to placebo."The collagen density in the dermis significantly increased and the fragmentation of the dermal collagen network significantly decreased already after 4 weeks of supplementation.I don't know why people say there's "no scientific evidence" when these were in the top 10 results on pubmed? In case of skin elasticity, one parameter out of three was significantly improved in the LMWCP group from the baseline after 12 weeks, while, compared with the placebo group, two parameters out of three in the LMWCP group were higher with significance after 12 weeks. Direct effects of collagen peptides on fibroblasts, M2- like macrophages, and oral tolerance-related mechanisms are the possible mechanisms for the beneficial effects of collagen supplementation." ĥ) "After 12 weeks in the Low-molecular-weight Collagen peptide group, visual assessment score and three parameters of skin wrinkling were significantly improved compared with the placebo group. With regard to skin moisture and skin evaporation, a positive influence of CH treatment could be observed in a subgroup analysis, but data failed to reach a level of statistical significance." ģ) "This study demonstrated that the use of the collagen hydrolysate with a higher content of Pro-Hyp and Hyp-Gly led to more improvement in facial skin conditions, including facial skin moisture, elasticity, wrinkles and roughness." Ĥ) This one is a review ". Both effects persisted after 12 weeks." Ģ) "At the end of the study, skin elasticity in both CH dosage groups showed a statistically significant improvement in comparison to placebo. The folks at ScA have put in a ton of time and effort into their resources, so take advantage of them!ġ) "The collagen density in the dermis significantly increased and the fragmentation of the dermal collagen network significantly decreased already after 4 weeks of supplementation.
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